Publications
Research and Articles
A comprehensive electromagnetic evaluation of an MRI anthropomorphic head phantom
December 22, 2020
A heterogenous refillable six‐compartment 3D‐printed human‐head phantom (established from MRI scans obtained in vivo) was compared with a homogeneous commercial spherical phantom, the phantom itself with homogeneous loading in all of its compartments, and in vivo. Detailed analysis is presented using computational and experimental evaluations of the magnetic and electric fields and the scattering parameters.
November 5, 2020
Sickle cell disease (SCD) is caused by hemoglobin S polymerization leading to vaso-occlusion, small vessel disease, and reduced tissue oxygen saturation. Noninvasive assessments and screening of small vessel disease and decreased oxygen saturation in select organs, like the brain, are poorly developed.
Improved 7 Tesla Transmit Field Homogeneity with Reduced Electromagnetic Power Deposition Using Coupled Tic Tac Toe Antennas
November 13, 2020
Recently cleared by the FDA, 7 Tesla (7T) MRI is a rapidly growing technology that can provide higher resolution and enhanced contrast in human MRI images. However, the increased operational frequency (~297 MHz) hinders its full potential since it causes inhomogeneities in the images and increases the power deposition in the tissues. This work describes the optimization of an innovative radiofrequency (RF) head coil coupled design, named Tic Tac Toe, currently used in large scale human MRI scanning at 7T; to date, this device was used in more than 1,300 patient/volunteer neuro 7T MRI scans.
Quantifying Cerebral Autoregulation in Patients with Sickle Cell Disease Using Near-Infrared Spectroscopy
April 5, 2020
This study aimed to quantify cerebral autoregulation (CA) in patients with sickle cell disease (SCD) (n=11) and healthy controls (n=14) using near-infrared spectroscopy. Patients and volunteers performed paced breathing and frequency-dependent phase differences were compared.
How to design and construct a 3D-printed human head phantom
August 21, 2019
In medical physics, phantoms are physical and/or numerical tools created to represent specified characteristics of human anatomy [1–5]. Phantoms are a less expensive approach for testing and validation of a variety of applications, such as communication or medical …
Computational and experimental evaluation of the Tic-Tac-Toe RF coil for 7 Tesla MRI
January 10, 2019
A variety of 7 Tesla RF coil systems have been proposed to produce spin excitation (B1+ field) and MR image acquisition. Different groups have attempted to mitigate the challenges at high and ultra-high field MRI by proposing novel hardware and software solutions to obtain uniformly high spin excitation at acceptable RF absorption levels. In this study, we extensively compare the designs of two distributed-circuit based RF coils: the Tic-Tac-Toe (TTT) head coil and TEM head coil on multiple anatomically detailed head models and in-vivo.
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